The biological abnormalities found in ME/CFS patients are in the immune system, brain, hormone levels, cardiovascular system, metabolism, infection activity and gene activity. As a multi-system disease, no one biological test is used for diagnosis.
with ME/CFS will often have different symptoms, possibly due
to which system is more affected in each patient, differing infection
activity in each patient and possibly the stage of the disease. The
symptoms may appear suddenly, sometimes as a wave coming over the person's body.
Or the symptoms may come gradually, over years. Infections, such as mononucleosis, are common triggers of ME/CFS.
While researchers and government health agencies use different diagnostic criteria, the following pattern of symptoms are now recognized as occurring in these patients:
A more complete list of symptoms can be seen here.
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